Human 5-HT_3A -- Pro 51

mPro56Ala

Mutation resulted in the ablation of specific binding. No labeling was observed when their localization was studied using an antiserum specific for the N terminus of the 5-HT_3A.

Deane CM, Lummis SCR (2001) The Role and Predicted Propensity of Conserved Proline Residues in the 5-HT3 Receptor. The Journal of Biological Chemistry 276(41):37962-37966

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