GABAA subunit b2

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

 

GABAA b2 - GENBANK

GABAA b2 - FASTA

GABAA b2 - Alignment

 

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Gly 244 Gln 25 Asp 26 Asp 27 Asp 28 Asp 29 Pro 30 Ser 31 Asn 32 Met 33 Ser 34 Leu 35 Val 36 Lys 37 Glu 38 Thr 39 Val 40 Asp 41 Arg 42 Leu 43 Leu 44 Lys 45 Gly 46 Tyr 47 Asp 48 Ile 49 Arg 50 Leu 51 Arg 52 Pro 53 Asp 54 Phe 55 Gly 56 Gly 57 Pro 58 Pro 59 Val 60 Ala 61 Val 62 Gly 63 Met 64 Asn 65 Ile 66 Asp 67 Ile 68 Ala 69 Ser 70 Ile 71 Asp 72 Met 73 Val 74 Ser 75 Glu 76 Val 77 Asn 78 Met 79 Asp 80 Tyr 81 Thr 82 Leu 83 Thr 84 Met 85 Tyr 86 Phe 87 Gln 88 Gln 89 Ala 90 Trp 91 Arg 92 Asp 93 Lys 94 Arg 95 Leu 96 Ser 97 Tyr 98 Asn 99 Val 100 Ile 100 Pro 102 Leu 103 Asn 104 Leu 105 Thr 106 Leu 107 Asp 108 Asn 109 Arg 110 Val 111 Ala 112 Asp 113 Gln 114 Leu 115 Trp 116 Val 117 Pro 118 Asp 119 Thr 120 Tyr 121 Phe 122 Leu 123 Asn 124 Asp 125 Lys 126 Lys 127 Ser 128 Phe 129 Val 130 His 131 Gly 132 Val 133 Thr 134 Val 135 Lys 136 Asn 137 Arg 138 Met 139 Ile 140 Arg 141 Leu 142 His 143 Pro 144 Asp 145 Gly 146 Gly 147 Val 148 Leu 149 Tyr 150 Gly 151 Leu 152 Arg 153 Ile 154 Thr 155 Thr 156 Thr 157 Ala 158 Ala 159 Cys 160 Met 161 Met 162 Asp 163 Leu 164 Arg 165 Arg 166 Tyr 167 Pro 168 Leu 169 Asp 170 Glu 171 Gln 172 Asn 173 Cys 174 Thr 175 Lys 176 Glu 177 Ile 178 Glu 179 Ser 180 Tyr 181 Gly 182 Tyr 183 Thr 184 Thr 185 Asp 186 Asp 187 Ile 188 Glu 189 Phe 190 Tyr 191 Trp 192 Arg 193 Gly 194 Asp 195 Asp 196 Asn 197 Ala 198 Val 199 Tyr 200 Gly 201 Val 202 Thr 203 Lys 204 Ile 205 Glu 206 Leu 207 Asp 208 Gln 209 Phe 210 Ser 211 Ile 212 Val 213 Asp 214 Tyr 215 Lys 216 Leu 217 Ile 218 Thr 219 Lys 220 Lys 221 Val 222 Val 223 Phe 224 Ser 225 Thr 226 Gly 227 Ser 228 Tyr 229 Pro 230 Arg 231 Leu 232 Ser 233 Leu 234 Ser 235 Phe 236 Lys 237 Leu 238 Lys 239 Arg 240 Asn 241 Ile 242 Gly 243

Residues with Mutations: [ Arg 51 ]

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M1

 

Tyr 243 Phe 244 Ile 245 Leu 246 Gln 247 Thr 248 Tyr 249 Met 250 Pro 251 Ser 252 Ile 253 Leu 254 Ile 255 Thr 256 Ile 257 Leu 258 Ser 259 Trp 260 Val 261 Ser 262 Phe 263 Trp 264

 

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M1-M2 Linker

 

 

Ile 265 Asn 266 Tyr 267 Asp 268 Ala 269

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M2

Ser 270 Ala 271 Ala 272 Arg 273 Val 274 Ala 275 Leu 276 Gly 277 Ile 278 Thr 279 Thr 280 Val 281 Leu 282 Thr 283 Met 284 Thr 285 Thr 286 Ile 287 Asn 265 Thr 289 His 290

Residues with Mutations: [ Asn 265 ] [ Leu 288 ]

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M2-M3 Linker

Leu 291 Arg 292 Glu 293 Thr 294 Leu 295 Pro 296 Lys 297 Ile 298 Pro 299 Tyr 300 Val 301 Lys 302

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M3

 

Ala 303 Ile 304 Asp 305 Met 306 Tyr 307 Leu 308 Met 309 Gly 310 Cys 311 Phe 312 Val 313 Phe 314 Val 315 Phe 316 Met 317 Ala 318 Leu 319 Leu 320 Glu 321 Tyr 322 Ala 323 Leu 324

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M3-M4 Linker

 

Val 325 Asn 326 Tyr 327 Ile 328 Phe 329 Phe 330 Gly 331 Arg 332 Gly 333 Pro 334 Gln 335 Arg 336 Gln 337 Lys 338 Lys 339 Ala 340 Ala 341 Glu 342 Lys 343 Ala 344 Ala 345 Ser 346 Ala 347 Asn 348 Asn 349 Glu 350 Lys 351 Met 352 Arg 353 Leu 354 Asp 355 Val 356 Asn 357 Lys 358 Ile 359 Phe 360 Tyr 361 Lys 362 Asp 363 Ile 364 Lys 365 Gln 366 Asn 367 Gly 368 Thr 369 Gln 370 Tyr 371 Arg 372 Ser 373 Leu 374 Trp 375 Asp 376 Pro 377 Thr 378 Gly 379 Asn 380 Leu 381 Ser 382 Pro 383 Thr 384 Arg 385 Arg 386 Thr 387 Thr 388 Asn 389 Tyr 390 Asp 391 Phe 392 Ser 393 Leu 394 Tyr 395 Thr 396 Met 397 Asp 398 Pro 399 His 400 Glu 401 Asn 402 Ile 403 Leu 404 Leu 405 Ser 406 Thr 407 Leu 408 Glu 409 Ile 410 Lys 411 Asn 412 Glu 413 Met 414 Ala 415 Thr 416 Ser 417 Glu 418 Ala 419 Val 420 Met 421 Gly 422 Leu 423 Gly 424 Asp 425 Pro 426 Arg 427 Ser 428 Tyr 429 Met 430 Lys 431 Ala 432 Tyr 433 Asp 434 Ala 435 Ser 436 Ser 437 Ile 438 Gln 439 Tyr 440 Arg 441 Lys 442 Ala 443 Gly 444

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M4

Leu 445 Pro 446 Arg 447 His 448 Ser 449 Phe 450 Gly 451 Arg 452 Asn 453 Ala 454 Lys 455 Glu 456 Arg 457 His 458 Val 459 Ala 460 Gln 461 Lys 462 Lys 463 Ser 464 Arg 465 Leu 466 Arg 467 Arg 468 Arg 469 Ala 470 Ser 471 Gln 472 Leu 473 Lys 474 Ile 475 Thr 476 Ile 477 Pro 478 Asp 479 leu 480 Thr 481 Asp 482 Val 483 Asn 484 Ala 485 Ile 486 Asp 487 Arg 488 Trp 489 Ser 490 Arg 491 Ile 492 Phe 493 Phe 494 Pro 495 Val 496 Val 497 Phe 498 Ser 499 Phe 500 Phe 501 Asn 502 Ile 503 Val 504 Tyr 505 Trp 506 Leu 507 Tyr 508 Tyr 509 Val 510 Asn 511

 

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Alignment