GABAA subunit a1

Click on sections of picture to learn more about research on individual amino acids. Numbering of the GABAA b3 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M4 M3-M4 Linker

GABAA a1 -- GENBANK

GABAA a1 -- FASTA

GABAA a1 -- Alignment

 

 

 

 

 

 

 

 

 

 

 

 

N-Terminus

Residues with Mutations: [ Arg 58 ]

Ser 30 Pro 29 Gln 28 Leu 31 Gln 32 Asp 33 Glu 34 Leu 35 Lys 36 Asp 37 Asn 38 Thr 39 Thr 40 Val 41 Phe 42 Thr 43 Arg 44 Ile 45 Leu 46 Asp 47 Arg 48 Leu 49 Leu 50 Asp 51 Gly 52 Tyr 53 Asp 54 Asn 55 Arg 56 Leu 57 Arg 58 Pro 59 Gly 60 Leu 61 Gly 62 Glu 63 Arg 64 Val 65 Thr 66 Glu 67 Val 68 Lys 69 Thr 70 Asp 71 Ile 72 Phe 73 Val 74 Thr 75 Ser 76 Phe 77 Gly 78 Pro 79 Val 80 Ser 81 Asp 82 His 83 Asp 84 Met 85 Glu 86 Tyr 87 Thr 88 Ile 89 Asp 90 Val 91 Phe 92 Phe 93 Arg 94 Gln 95 Ser 96 Trp 97 Lys 98 Asp 99 Glu 100 Arg 101 Leu 102 Lys 103 Phe 104 Lys 105 Gly 106 Pro 107 Met 108 Thr 109 Val 110 Leu 111 Arg 112 Leu 113 Asn 114 Asn 115 Leu 116 Met 117 Ala 118 Ser 119 Lys 120 Ile 121 Trp 122 Thr 123 Pro 124 Asp 125 Thr 126 Phe 127 Phe 128 His 129 Asn 130 Gly 131 Lys 132 Lys 133 Ser 134 Val 135 Ala 136 His 137 Asn 138 Met 139 Thr 140 Met 141 Pro 142 Asn 143 Lys 144 Leu 145 Leu 146 Arg 147 Ile 148 Thr 149 Glu 150 Asp 151 Gly 152 Thr 153 Leu 154 Leu 155 Tyr 156 Thr 157 Met 158 Arg 159 Leu 160 Thr 161 Val 162 Arg 163 Ala 164 Glu 165 Cys 166 Pro 167 Met 168 His 169 Leu 170 Glu 171 Asp 172 Phe 173 Pro 174 Met 175 Asp 176 Ala 177 His 178 Ala 179 Cys 180 Pro 181 Leu 182 Lys 183 Phe 184 Gly 185 Ser 186 Tyr 187 Ala 188 Tyr 189 Thr 190 Arg 191 Ala 192 Glu 193 Val 194 Val 195 Tyr 196 Glu 197 Trp 198 Thr 199 Arg 200 Glu 201 Pro 202 Ala 203 Arg 204 Ser 205 Val 206 Val 207 Val 208 Ala 209 Glu 210 Asp 211 Gly 212 Ser 213 Arg 214 Leu 215 Asn 216 Gln 217 Tyr 218 Asp 219 Leu 220 Leu 221 Gly 222 Gln 223 Thr 224 Val 225 Asp 226 Ser 227 Gly 228 Ile 229 Val 230 Gln 231 Ser 232 Ser 233 Thr 234 Gly 235 Glu 236 Gly 237 Val 238 Val 239 Met 240 Thr 241 Thr 242 His 243 Phe 244 His 245 Leu 246 Lys 247 Arg 248 Lys 249 Ile 250 Gly 251 back to top

 

M1

Tyr 252 Phe 253 Val 254 Ile 255 Gln 256 Thr 257 Tyr 258 Leu 259 Pro 260 Cys 261 Ile 262 Met 263 Thr 264 Val 265 Ile 266 Leu 267 Ser 268 Gln 269 Val 270 Ser 271 Phe 272 Trp 273

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M1-M2 Linker

Leu 274 Asn 275 Arg 276 Glu 277 Ser 278 back to top

 

M2

Val 279 Pro 280 Ala 281 Arg 282 Thr 283 Val 284 Phe 285 Gly 286 Val 287 Thr 288 Thr 289 Val 290 Leu 291 Thr 292 Met 293 Thr 294 Thr 295 Leu 296 Ser 297 Ile 298 Ser 299 back to top

 

M2-M3 Linker

Ala 300 Arg 301 Asn 302 Ser 303 Leu 304 Pro 305 Lys 306 Val 307 Ala 308 Tyr 309 Ala 310 Thr 311 back to top

 

M3

Residues with Mutations: [ Ala 322 ]

Ala 312 Met 313 Asp 314 Trp 315 Phe 316 Ile 317 Ala 318 Val 319 Cys 320 Tyr 321 Ala 322 Phe 323 Val 324 Phe 325 Ser 326 Ala 327 Leu 328 Ile 329 Glu 330 Phe 331 Ala 332 Thr 333 back to top

 

M3-M4 Linker

Val 334 Asn 335 Tyr 336 Phe 337 Thr 338 Lys 339 Arg 340 Gly 341 Tyr 342 Ala 343 Trp 344 Asp 345 Gly 346 Lys 347 Ser 348 Val 349 Val 350 Pro 351 Glu 352 Lys 353 Pro 354 Lys 355 Lys 356 Val 357 Lys 358 Asp 359 Pro 360 Leu 361 Ile 362 Lys 363 Lys 364 Asn 365 Asn 366 Thr 367 Tyr 368 Ala 369 Pro 370 Thr 371 Ala 372 Thr 373 Ser 374 Tyr 375 Thr 375 Pro 377 Asn 378 Leu 379 Ala 380 Arg 381 Gly 382 Asp 383 Pro 384 Gly 385 Leu 386 Ala 387 Thr 388 Ile 389 Ala 390 Lys 391 Ser 392 Ala 393 Thr 394 Ile 395 Glu 396 Pro 397 Lys 398 Glu 399 Val 400 Lys 401 Pro 402 Glu 403 Thr 404 Lys 405 Pro 406 Pro 407 Glu 408 Pro 409 Lys 410 Lys 411 Thr 412 Phe 413 Asn 414 Ser 415 Val 416 Ser 417 Lys 418 Ile 419 Asp 420 Arg 421

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M4

Leu 422 Ser 423 Arg 424 Ile 425 Ala 426 Phe 427 Pro 428 Leu 429 Leu 430 Phe 431 Gly 432 Ile 433 Phe 434 Asn 435 Leu 436 Val 437 Tyr 438 Trp 439 Ala 440 Thr 441 Tyr 442 Leu 443 Asn 444 Arg 445 Glu 446 Pro 447 Gln 448 Leu 449 Lys 450 Ala 451 Pro 452 Thr 453 Pro 454 His 455 Gln 456

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Alignment