nACh subunit b

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh b subunit sequences start at the beginning of the mature protein. Only amino acids in the mature protein are shown.

amino acid all N-Terminus M1 M1-M2 Linker M2 M2-M3 Linker M3 M3-M4 Linker M4

nACh b -- GENBANK

nACh b -- FASTA

nACh b -- Alignment

 

 

 

 

 

 

 

 

N-Terminus

Ser 1 Val 19 Arg 20 Pro 21 Ala 22 Arg 23 Glu 24 Val 25 Gly 26 Asp 27 Arg 28 Val 29 Arg 30 Val 31 Ser 32 Val 33 Gly 34 Leu 35 Ile 36 Leu 37 Ala 38 Gln 39 Leu 40 Ile 41 Ser 42 Leu 43 Asn 44 Glu 45 Lys 46 Asp 47 Glu 48 Glu 49 Met 50 Ser 51 Thr 52 Lys 53 Val 54 Tyr 55 Leu 56 Asp 57 Leu 58 Glu 59 Trp 60 Thr 61 Asp 62 Tyr 63 Arg 64 Leu 65 Ser 66 Trp 67 Asp 68 Pro 69 Ala 70 Glu 71 His 72 Asp 73 Gly 74 Ile 75 Asp 76 Ser 77 Leu 78 Arg 79 Ile 80 Thr 81 Ala 82 Glu 83 Ser 84 Val 85 Trp 86 Leu 87 Asp 88 Pro 89 Val 90 Val 91 Leu 92 Leu 93 Asn 94 Asn 95 Asn 96 Asp 97 Gln 98 Asn 99 Phe 100 Asp 101 Val 102 Ala 103 Leu 104 Asp 105 Ile 106 Ser 107 Val 108 Val 109 Val 110 Ser 111 Ser 112 Asp 113 Gly 114 Ser 115 Val 116 Arg 117 Trp 118 Gln 119 Pro 120 Pro 121 Gly 122 Ile 123 Tyr 124 Arg 125 Ser 126 Ser 127 Cys 128 Ser 129 Ile 130 Gln 131 Val 132 Thr 133 Tyr 134 Phe 135 Pro 136 Phe 137 Asp 138 Trp 139 Gln 140 Asn 141 Cys 142 Thr 143 Met 144 Val 145 Phe 146 Ser 147 Ser 148 Tyr 149 Ser 150 Tyr 151 Asp 152 Ser 153 Ser 154 Glu 155 Val 156 Ser 157 Leu 158 Gln 159 Thr 160 Gly 161 Leu 162 Gly 163 Pro 164 Asp 165 Gly 166 Gln 167 Gly 168 His 169 Gln 170 Glu 171 Ile 172 His 173 Ile 174 His 175 Glu 176 Gly 177 Thr 178 Phe 179 Ile 180 Glu 181 Asn 182 Gly 183 Gln 184 Trp 185 Glu 186 Ile 187 Ile 188 His 189 Lys 190 Pro 191 Ser 192 Arg 193 Leu 194 Ile 195 Gln 196 Pro 197 Pro 198 Glu 199 Asn 200 Pro 201 Arg 202 Gly 203 Gly 204 Arg 205 Glu 206 Gly 207 Gln 208 Arg 209 Gln 210 Glu 211 Val 212 Ile 213 Phe 214 Tyr 215 Leu 216 Ile 217 Ile 218 Arg 219 Arg 220 Lys 221 Pro 222 Ser 18 Ser 17 Asp 16 Asn 15 Gly 14 Ser 13 Phe 12 Leu 11 Lys 10 Glu 9 Arg 8 Leu 7 Arg 6 Gly 5 Glu 4 Ala 3 Glu 2

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M1

Tyr 245 Phe 244 Val 243 Phe 242 Ile 241 Ala 240 Leu 239 Leu 238 Thr 237 Ile 236 Leu 235 Ile 234 Cys 233 Pro 232 Ala 231 Ile 230 Val 229 Asn 228 Val 227 Leu 226 Tyr 225 Phe 224 Lys 223

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M1-M2 Linker

Leu 246 Pro 247 Pro 248 Asp 249 Ala 250 Gly 251 Glu 252 Lys 253

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M2

Met 254 Gly 255 Leu 256 Ser 257 Ile 258 Phe 259 Ala 260 Leu 261 Leu 262 Thr 263 Leu 264 Thr 265 Val 266 Phe 267 Leu 271 Ala 272 Leu 270 Leu 269 Leu 268

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M2-M3 Linker

Asp 273 Lys 274 Val 275 Pro 276 Glu 277 Thr 278 Ser 279 Leu 280 Ser 281 Val 282

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M3

Pro 283 Ile 284 Ile 285 Ile 286 Lys 287 Tyr 288 Leu 289 Met 290 Phe 291 Thr 292 Met 293 Val 294 Leu 295 Val 296 Thr 297 Phe 298 Ser 299 Val 300 Ile 301

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M3-M4 Linker

Trp 450 Leu 449 Phe 448 Leu 447 Arg 446 Asp 445 Val 444 Val 443 Met 442 Arg 441 Val 440 Phe 439 Leu 433 Lys 434 Glu 435 Asp 436 Trp 437 Gln 438 Ala 432 Asp 431 His 430 Asp 429 Glu 428 Gln 427 Phe 384 Gln 385 Pro 386 Glu 387 Leu 388 Ser 389 Ala 390 Pro 391 Asp 392 Leu 393 Arg 394 Arg 395 Phe 396 Ile 397 Asp 398 Gly 399 Pro 400 Asn 401 Arg 402 Ala 403 Val 404 Ala 405 Leu 406 Leu 407 Pro 408 Glu 409 Leu 410 Arg 411 Glu 412 Val 413 Val 414 Ser 415 Ser 416 Ile 417 Ser 418 Tyr 419 Ile 420 Arg 370 Lys 371 Pro 372 Pro 373 Ser 374 Asp 375 Phe 376 Phe 378 Leu 377 Pro 379 Lys 380 Pro 381 Asn 382 Arg 383 Gln 425 Glu 426 Leu 424 Gln 423 Ala 421 Arg 422 Leu 376 Ile 369 Phe 368 Tyr 367 Glu 366 Asp 365 Thr 364 Gly 363 Arg 362 Gly 361 Trp 360 Gly 359 Ser 358 Gly 357 Pro 356 Ser 355 Ser 354 Cys 353 His 352 Pro 351 Pro 350 Glu 349 Pro 348 Met 347 Leu 346 Asp 345 Arg 344 Glu 343 Pro 342 Pro 340 Lys 341 Arg 339 Lys 338 Leu 337 Arg 336 Leu 335 Tyr 334 Leu 333 Pro 332 Leu 331 Lys 330 His 329 Ile 328 Phe 327 Ile 326 Gln 325 Arg 324 Val 323 Trp 322 Leu 321 Pro 320 Gln 318 Met 319 His 317 Thr 316 His 315 Pro 314 Ser 313 Arg 312 His 311 His 310 Leu 309 Asn 308 Leu 307 Val 306 Val 305 Val 304 Ser 303 Leu 302

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M4

Thr 451 Phe 452 Ile 453 Ile 454 Phe 455 Thr 456 Ser 457 Val 458 Gly 459 Thr 460 Leu 461 Val 462 Ile 463 Phe 464 Leu 465 Asp 466 Ala 467 Thr 468 Tyr 469 His 470 Leu 471 Pro 472 Pro 473 Pro 474 Asp 475 Phe 476 Pro 477 Phe 478

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus