nACh subunit b4

Click on sections of picture to learn more about research on individual amino acids. Numbering of the nACh b4 subunit sequences start at the beginning of the signal sequence. Only amino acids in the mature protein are shown.

amino acid all M2-M3 Linker M3-M4 Linker M2 M4 M3 M1-M2 Linker N-Terminus M1 .

nACh b4 -- GENBANK

nACh b4 -- FASTA

nACh b4 -- Alignment

 

 

 

 

 

 

 

 

 

 

N-Terminus

Pro 185 Leu 186 Tyr 188 Phe 187 Thr 189 Lys 184 Thr 1 Ser 2 Ser 3 Ser 4 Gln 5 Leu 6 Ile 7 Ser 8 Ile 9 Lys 10 Leu 11 Gln 12 Gln 36 Lys 35 Leu 34 Trp 33 Val 32 Asn 31 Thr 30 Thr 29 Met 28 Ile 27 Gln 26 Glu 25 Arg 24 Glu 23 Asn 22 Val 21 Ser 20 Ile 19 Leu 18 Gln 17 Ala 16 Leu 15 Ser 14 Leu 13 Ala 60 Pro 59 Ile 58 Arg 57 Leu 56 Ile 55 Asn 54 Val 53 Gly 52 Glu 51 Tyr 50 Arg 49 Ser 48 Ser 47 Asn 46 Trp 45 Tyr 44 Leu 43 Arg 42 Tyr 41 Asp 40 Thr 39 Trp 38 Glu 37 Lys 61 Tyr 83 Leu 86 Asn 85 Thr 84 Val 82 Ser 81 Val 80 Glu 79 Tyr 78 Thr 77 Gly 76 Asp 75 Ala 74 Asn 73 Asn 72 Tyr 71 Leu 70 Val 69 Ile 68 Asp 67 Pro 66 Leu 65 Trp 64 Ile 63 Arg 62 Val 110 Glu 109 Ile 108 Lys 107 Cys 106 Ala 105 Ser 104 Lys 103 Tyr 102 Ile 101 Ala 100 Pro 99 Ser 93 Val 94 Leu 95 Trp 96 Pro 98 Leu 97 Glu 92 Asn 91 Ser 90 Arg 89 Val 88 Ile 87 His 131 Asp 130 Tyr 129 Thr 128 Trp 127 Ser 126 Arg 125 Phe 124 Lys 123 Leu 122 Thr 121 Cys 120 Asn 119 Gln 118 Gln 117 Asp 116 Phe 115 Pro 114 Phe 113 Tyr 112 Lys 111 Thr 132 Glu 133 Ile 134 Asp 135 Met 136 Asp 155 Trp 154 Glu 153 Gly 152 Ser 151 Pro 150 Thr 149 Phe 148 Asp 147 Asp 146 Met 145 Ser 144 Ala 143 Thr 142 Pro 141 Thr 140 Met 139 Leu 138 Val 137 Tyr 177 Thr 176 Val 175 Asp 174 Val 173 Tyr 172 Ser 171 Pro 170 Asp 169 Gln 168 Pro 167 Asn 166 Val 165 Thr 164 Arg 163 Arg 162 Gly 161 Pro 160 Leu 159 Ile 156 Val 157 Ala 158 Asp 178 Phe 179 Ile 181 Ile 180 Lys 182 Arg 183

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M1

Pro 210 Leu 209 Tyr 208 Phe 207 Val 206 Leu 205 Ile 204 Ala 203 Leu 202 Leu 201 Thr 200 Thr 199 Leu 198 Val 197 Cys 196 Pro 195 Ile 194 Ile 193 Leu 192 Asn 191 Ile 190

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M1-M2 Linker

Leu 219 Ser 211 Asp 212 Cys 213 Gly 214 Glu 215 Lys 216 Met 217 Thr 218

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M2

Pro 240 Pro 239 Cys 220 Ile 221 Ser 222 Val 223 Leu 224 Thr 228 Leu 227 Ala 226 Leu 225 Phe 229 Phe 230 Leu 231 Leu 232 Leu 233 Ile 234 Ser 235 Lys 236 Ile 237 Val 238

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M2-M3 Linker

Tyr 251 Thr 241 Ser 242 Leu 243 Asp 244 Val 245 Pro 246 Leu 247 Ile 248 Gly 249 Lys 250

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M3

Val 272 Asn 271 Leu 252 Met 253 Phe 254 Thr 255 Met 256 Val 257 Leu 258 Val 259 Thr 260 Phe 261 Ser 262 Ile 263 Val 264 Thr 265 Ser 266 Val 267 Cys 268 Val 269 Leu 270

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M3-M4 Linker

Leu 414 Arg 413 Asp 412 Val 411 Val 410 Met 409 Ala 408 Val 407 Tyr 406 Lys 405 Trp 404 Asp 403 Glu 402 Val 401 Val 400 Ser 399 Asp 397 Gln 398 Glu 396 Asp 395 Asp 394 Asn 393 Lys 392 Met 391 His 390 Gln 389 Ala 388 Ala 348 Ile 387 Phe 386 Ser 385 Val 384 Gly 383 Glu 382 Leu 381 Ala 380 Thr 357 Glu 379 Gln 378 Val 377 Asp 376 Gln 375 Arg 374 Phe 373 Arg 372 Gly 371 Pro 358 Val 359 Ala 360 Ile 361 Pro 362 Arg 363 Phe 299 Met 300 Lys 301 Arg 302 Pro 303 Gly 304 Pro 305 Asp 306 Ser 307 Ser 308 Pro 309 Ala 310 Arg 311 Ala 312 Phe 313 Pro 314 Pro 315 Ser 316 Lys 317 Ser 318 Cys 319 Val 320 Thr 321 Lys 322 Pro 323 Glu 324 Ala 325 Thr 326 Ala 327 Thr 328 Ser 329 Thr 330 Ser 331 Pro 332 Ser 333 Asn 334 Phe 335 Tyr 336 Gly 337 Asn 338 Ser 339 Met 340 Tyr 341 Phe 342 Val 343 Asn 344 Pro 345 Ala 346 Ser 347 Ala 349 Ser 350 Lys 351 Ser 352 Pro 353 Ala 354 Gly 355 Ser 356 Asp 364 Phe 365 Trp 366 Leu 367 Arg 368 Ser 369 Ser 370 Leu 298 Phe 297 Thr 296 Pro 295 Leu 294 Lys 293 His 292 Leu 291 Phe 290 Cys 289 Arg 288 Lys 287 Val 286 Trp 285 Pro 284 Ala 283 Met 282 Thr 281 His 280 Thr 279 Ser 278 Pro 277 Ser 276 Arg 275 His 274 His 273

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M4

Phe 415 Leu 416 Trp 417 Val 418 Phe 419 Met 420 Phe 421 Val 422 Cys 423 Val 424 Leu 425 Gly 426 Thr 427 Val 428 Gly 429 Leu 430 Phe 431 Leu 432 Pro 433 Pro 434 Leu 435 Phe 436 Gln 437 Thr 438 His 439 Ala 440 Ala 441 Ser 442 Glu 443 Gly 444 Pro 445 Tyr 446 Ala 447 Ala 448 Gln 449 Arg 450 Asp 451

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Alignment

N-Terminus First Membrane Spanning Second Membrane Spanning Third Membrane Spanning Outside the Cell Inside the Cell C-Terminus